EpimiRNA
Bicoll © Kai Lamottke
Bicoll © Kai Lamottke

Partner 2B - Philipps Universität Marburg- Prof. Gerhard Schratt

 

Gerhardt Schratt

Prof. Dr. med. Gerhard Schratt

Director

Phone: +49 221 478 4005

Fax: +49 221 478 87139

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Philipps Universität Marburg

Insitute of Physiological Chemistry

Karl-von-Fisch-Str. 1

35032 Marburg

Germany

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EpimiRNA Team BPC (biochemical-pharmacological center)

Roberto_Fiore

Dr. Roberto Fiore

PostDoc/ Imaging effects of miRNAs in   neurons, neuronal morphology, microscopy

Phone: +49 6421 28 62289

Fax: +49 6421 28 65957

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Ayla_Askoy-Aksel

Dr. Ayla Aksel-Aksoy

Expertise in electrophysiology

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Eva Becker

Technical Assistant (Molecular biology)

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Gertraud Jarosch

Technical Assistant (Cell culture, molecular transfections)

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From left to right: Roberto Fiore, Ayla Aksel-Aksoy

and Gerhard Schratt.

Institute presentation

The Institute for Physiological Chemistry (IPC) is one of the leading laboratories in the field of neuronal microRNA research worldwide. They identified the first brain-specific microRNA that is involved synaptic plasticity by regulating the size of neuronal dendritic spines (Schratt et al., Nature 2006). The IPC recently contributed to the identification of additional microRNAs and the underlying signaling mechanisms involved in neuroplasticity in the cortex, hippocampus and striatum (Fiore et al., 2009; Siegel et al., 2009; Saba et al., 2012). Prof. Schratt is a recipient of an ERC Starting Grant (NEUROMIR; microRNA function in homeostatic plasticity with implications for neuropsychiatric disorders) and coordinator of a Priority Program on “Emerging roles of non-coding RNAs in nervous system development, plasticity and disease” funded by the German Research Foundation (DFG). Established key technologies at the IPC include high-resolution fluorescence confocal microscopy, intracerebral injection of recombinant adeno-associated virus in living rats/mice, electrophysiological recordings and the analysis of small RNA deep sequencing data. 

 

 

 

EpimiRNA Team

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