RCSI is Ireland’s largest Medical School but also has a thriving post-graduate school with over 100 active PhD students as well as other advanced degrees. The RCSI Research Institute is one of Ireland’s foremost translational and clinical research institutions comprising 75 principal investigators and core facilities for genomics, proteomics, imaging and biobanking and the platforms for microRNA profiling from tissue and biofluids.
Prof. Henshall is the Director of the Experimental Epilepsy Research group at RCSI (http://pi.rcsi.ie/pi/dhenshall/). His team currently comprises 10 researchers whose major research focuses include the role of non-coding RNA (including microRNA) in the development of epilepsy, the modelling and treatment of neonatal seizures, ATP-gated ion channels as targets for seizure control, and molecular biomarkers of epilepsy. Henshall is aslo Co-Director of The Centre for the Study of Neurological Disorders (www.rcsi.ie/csnd), also based at RCSI. The Centre comprises investigators working on acute and chronic CNS diseases, including epilepsy, stroke and Alzheimer’s disease. The Centre features dedicated facilities and specialized equipment including EEG, biobanking, cognitive testing and two-photon microscopy.
Clinical aspects of the research are conducted in association with Beaumont hospital and RCSI’s Education and Research Centre. The co-localisation of the Centre with the national centre for the evaluation and surgical treatment of chronic pharmacoresistant epilepsy facilitates recruitment of patients and integration of clinical and research teams.